Comparison · Regulated B2B Tech & SoftwareSEQUESTO vs Loopio for Regulated B2B Tech & Software
Regulated customers send a 400-row requirement matrix, a security annex, a data processing agreement and their regulator's questions, often in one tender. Loopio answers the questions from a library of approved answers. SEQUESTO runs the whole bid: James answers from your current product docs and policies in the buyer's own file, lists the DPA clauses that differ from your terms, and shows how every answer was built.
Honest Positioning
Where Each Platform Shines for Regulated Tech
Loopio is a good fit if you…
SEQUESTO is a better fit if you…
Common Frustrations
Where Loopio Runs Out of Room for Regulated Tech
Based on Loopio's own published material, checked November 2026. In our view, these are the moments where a library-first tool asks the most of a bid team selling software to regulated buyers.
The Product Moves Faster Than the Library
A feature shipped last month is still "on the roadmap" in the answer library; a feature retired last year is still "standard". A library only stays current if someone keeps it current. James drafts each requirement and security answer from the documents you point him at, product docs, release notes, policies and past responses, so the answers change when your documentation does. No separate library to keep current.
A Regulated Buyer Sends More Than a Questionnaire
An IT tender from a bank or a public body comes with a requirement matrix, a security annex, a data processing agreement and, more and more, DORA or NIS2 questions, in Excel, Word and PDF. Loopio answers the questions and exports back to the buyer's Word or Excel file, not to PDF. James summarises the tender, answers the matrix with the buyer's compliance levels, lists the DPA clauses that differ from your standard terms for legal, fills every file in its own format and checks every requirement before the bid is called complete.
Your Customers' Auditors Want to See the Reasoning
Regulated customers ask how an answer was produced, and rules such as the EU AI Act expect AI used in business to be traceable. Loopio flags AI-composed answers, cites their sources and scores their confidence. SEQUESTO also shows how James built each answer, step by step, and records every edit, access change and approval with the person and the time, so you can show a customer's auditor the whole path from source to sign-off.
Feature Comparison · Checked November 2026
SEQUESTO vs Loopio for Regulated Tech, Feature by Feature
Requirement Matrices, Security and Regulation
Every Stage, Not Only the Answers
Built Around Your Team, Traceable to the Source
Where Loopio Wins
Loopio is a long-established vendor with a mature answer library, integrations with Salesforce, HubSpot, Dynamics and Microsoft 365 Copilot, and a browser extension that fills online procurement portals. It holds ISO 27001 and ISO 42001 certification, the standard for AI management systems, and a SOC 2 Type II report. Users rate it 4.6 out of 5 on G2. For a sales-led team answering security questionnaires in Excel and in portals, it does the job. But a regulated buyer's tender is more than a questionnaire. SEQUESTO runs the whole bid.
Migration
Switching From Loopio: How It Works
Bring Your Loopio Library, If You Want
Export your Loopio library and past responses if you want to keep them. You don't have to: SEQUESTO works from any file, product docs, release notes, policies and past responses, with no question-and-answer pairs to build first.
Connect Your Product Documentation
Upload or connect your product docs, release notes, security policies and past responses, in any format and any language, from SharePoint or Google Drive. Everything is indexed automatically: no preprocessing, no tagging, no mapping answers to questions.
We Tailor It to You
Our team does this step for you. In a one-hour session you walk us through how you work, and we set the aOS up around it: your stages, who handles the rows James cannot answer, your tone of voice, your personas, the properties you track and your dashboards. Nothing to build on your side. Included on every plan.
Start a Full Tender the Next Day
Documents uploaded, one hour with us, and the aOS can be ready the next day, set up properly around your process. Then start on a live tender: James answers the requirement matrix and the security annex, and your experts review only what needs them.
Bring Your Loopio Library, If You Want
Export your Loopio library and past responses if you want to keep them. You don't have to: SEQUESTO works from any file, product docs, release notes, policies and past responses, with no question-and-answer pairs to build first.
Connect Your Product Documentation
Upload or connect your product docs, release notes, security policies and past responses, in any format and any language, from SharePoint or Google Drive. Everything is indexed automatically: no preprocessing, no tagging, no mapping answers to questions.
We Tailor It to You
Our team does this step for you. In a one-hour session you walk us through how you work, and we set the aOS up around it: your stages, who handles the rows James cannot answer, your tone of voice, your personas, the properties you track and your dashboards. Nothing to build on your side. Included on every plan.
Start a Full Tender the Next Day
Documents uploaded, one hour with us, and the aOS can be ready the next day, set up properly around your process. Then start on a live tender: James answers the requirement matrix and the security annex, and your experts review only what needs them.
See Your Next IT Tender Run in SEQUESTO
In 30 minutes we answer your requirement matrix from your product documentation, in the buyer's own file.
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SEQUESTO vs AutoRFP.ai
Compare the SEQUESTO aOS - agentic bid management software for the full operation from intake to submission - with AutoRFP.ai, AI-native RFP response software with published project pricing and a portal browser extension.
SEQUESTO vs Microsoft Copilot
See how purpose-built proposal AI compares with general-purpose Copilot for RFP and bid management teams.
Use cases
Explore use cases
Security Questionnaire Response
Agents draft cited answers in any format, from SIG and CAIQ to custom questionnaires, and route them through your approval chain.
Explore Security Questionnaire Response →
Compliance Questionnaire Response
Automate compliance questionnaire responses at scale. Always up-to-date with live policy sync, first drafts from your approved policies, full audit trail for every submission.
Explore →
Tender Management
Agents parse the tender, surface the right knowledge per section and draft compliant answers. Your team validates, refines and approves.
Explore →FAQ
Frequently Asked Questions
In our view, SEQUESTO, when your customers send full tenders rather than only questionnaires. Both answer security questionnaires such as SIG and CAIQ. SEQUESTO also answers requirement matrices from your current product documentation, lists the DPA clauses that differ from your terms, fills the buyer's Word and PDF forms and shows how every answer was built. Loopio fits a sales-led team answering questionnaires in Excel and in procurement portals.
James drafts from the documents you point him at, such as current product docs and release notes, so answers change when your documentation changes. There is no separate library to maintain. Rows he cannot answer from the sources are marked "Needs review" and assigned to the right product manager, architect or security lead.
SIG, CAIQ, DORA, NIS2 and any customer spreadsheet, Word or PDF questionnaire, filled in the customer's own file, with dropdowns and sheet protection intact.
SEQUESTO. Every answer James drafts is traceable to the product doc, policy or past response it came from, with how it was built, step by step, and the audit trail records each edit, access change and approval. That gives your team, and your customers' auditors, the traceability that rules such as the EU AI Act expect of AI used in business.
In the EU or the US, as the customer chooses when the account is created, on every plan; the choice cannot be changed later. The AI runs in the same region, with full tenant isolation. Customer data is never used to train AI models. SEQUESTO is ISO 27001 certified and SOC 2 Type II audited.
Yes, if you want to. Export the library and past responses and drop them into the Knowledge Hub, which accepts Excel, Word, PDF, images and slide decks and indexes them automatically. It isn't required: SEQUESTO drafts from your current product docs, release notes and policies, without question-and-answer pairs. Switching can go fast: upload your documents, walk us through your process in a one-hour session, and our team configures the aOS around your process, tone of voice, personas, properties and dashboards. It can be ready the next day. Onboarding is included on every plan.